Lewandowicz-Uszyńska Aleksandra, Jankowski Adam
III Katedra Pediatrii Klinika Immunologii i Reumatologii Wieku Rozwojowego AM we Wrocławiu.
Pol Merkur Lekarski. 2011 Jun;30(180):409-12.
In this paper we present indications for use of intravenous immunoglobulins (IVIG). The role of IVIG in the therapy of immunodeficiency of IgG subclasses was underlined. The goal of the treatment is to obtain the immunoglobulin serum level sufficient to prevent patients against infections. The active component of IVIG is immunoglobulin G. The IVIG supplementation is required for agammaglobulinemia, common variable immunodeficiency diseases and some other serious immunodeficience. The probable side-effects of IVIG infusions are those associated with proteins transfusions, therefore the special caution during the infusion is required. However, the modern IVIG preparations are highly purified. The IVIG production techniques protect immunoglobulins against any unwanted changes and the procedures ensure patients against transmission of infections and unwanted reactions.
在本文中，我们介绍了静脉注射免疫球蛋白（IVIG）的使用指征。强调了IVIG在IgG亚类免疫缺陷治疗中的作用。治疗的目标是使血清免疫球蛋白水平足以预防患者感染。IVIG的活性成分是免疫球蛋白G。对于无丙种球蛋白血症、常见可变免疫缺陷疾病和其他一些严重免疫缺陷，需要补充IVIG。IVIG输注可能的副作用是那些与输血相关的副作用，因此在输注过程中需要特别小心。然而，现代IVIG制剂是高度纯化的。IVIG生产技术可保护免疫球蛋白免受任何不必要的变化，并且这些程序可确保患者不会发生感染传播和不良反应。
