Korsak Jolanta
Wojskowy Instytut Medyczny w Warszawie, Zakład Transfuzjologii Klinicznej CSK MON.
Pol Merkur Lekarski. 2011 Jun;30(180):430-4.
Intravenous immunoglobulins (IVIG) have been used mainly as a supplement therapy in hypogammglobulinemia patients. IVIG have been proved effective in treating TTP and recently they have been used in treating many autoimmune and inflammatory diseases. In neurologic diseases IVIG have immunomodulating features dependent on IgG Fc-fragment. Which diseases benefit from the use of IVIG was the find from controlled clinical trials in accordance with Evidence Based Medicine. IVIG have been proved effective in Guillaine-Barre syndrom, chronic inflammatory demyelinating polyradiculoneuropathy, miastenia, dermathomyositis and sclerosis multiple. The recommendations include the frequency of IVIG administering its dosage and duration of treatment.
静脉注射免疫球蛋白（IVIG）主要用作低丙种球蛋白血症患者的补充疗法。IVIG已被证明对治疗血栓性血小板减少性紫癜有效，最近还被用于治疗多种自身免疫性和炎性疾病。在神经系统疾病中，IVIG具有依赖于IgG Fc片段的免疫调节特性。根据循证医学，哪些疾病能从IVIG的使用中获益是通过对照临床试验得出的结论。IVIG已被证明对格林-巴利综合征、慢性炎症性脱髓鞘性多发性神经根神经病、重症肌无力、皮肌炎和多发性硬化症有效。这些建议包括IVIG给药的频率、剂量和治疗持续时间。
