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终末期肝病模型（MELD）是否需要修改？

Does model for end-stage liver disease (MELD) require modification?

作者信息

Desai H G

机构信息

Jaslok Hospital and Research Centre, Dr G Deshmukh Marg, Mumbai 400 026.

出版信息

J Assoc Physicians India. 2011 Jun;59:372-3.

PMID:21751591
Abstract

Model for End-stage Liver Disease (MELD) measures serum bilirubin (mg/dL), serum albumin (g/dL), International Normalised Ratio (INR) for prothrombin time. MELD score accurately predicts survival in 3 months for cirrhotic patients on the waiting list of liver transplantation. In about 15% of patients, it does not accurately predict survival and hence MELD-Na is recommended. MELD score is a poor predictor of survival after liver transplantation. Downgrading of MELD score for age of recipient and chance of recurrence of the disease is recommended to accurately predict survival after liver transplantation.

摘要

终末期肝病模型（MELD）测量血清胆红素（mg/dL）、血清白蛋白（g/dL）、凝血酶原时间的国际标准化比值（INR）。MELD评分能准确预测肝硬化患者在肝移植等待名单上3个月内的生存率。约15%的患者中，它不能准确预测生存率，因此推荐使用MELD-Na。MELD评分对肝移植后的生存率预测不佳。建议根据受者年龄和疾病复发几率对MELD评分进行下调，以准确预测肝移植后的生存率。

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Does model for end-stage liver disease (MELD) require modification?终末期肝病模型（MELD）是否需要修改？
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