肝脂肪瘤和脂肪变性：偶然之外的关联。
Hepatic lipomas and steatosis: an association beyond chance.
机构信息
Department of Radiology, Dr Peset University Hospital, Avda Gaspar Aguilar 90, 46017 Valencia, Spain.
出版信息
Eur J Radiol. 2012 Apr;81(4):e491-4. doi: 10.1016/j.ejrad.2011.06.018. Epub 2011 Jul 12.
OBJECTIVE
To determine if hepatic lipomas have a higher prevalence of liver steatosis than other benign hepatic lesions.
MATERIALS AND METHODS
Ninety-two benign hepatic lesions were analyzed with magnetic resonance (MR) imaging. There were 6 lipomas and 86 benign non-lipomatous lesions, including 55 hemangiomas, 23 focal nodular hyperplasias (FNH) and 8 adenomas. All studies included a chemical shift T1-weighted sequence (in-phase and opposed-phase) in order to evaluate the presence of steatosis.
RESULTS
A statistically significant relationship (Fischer's Exact Test, p=0.019) between hepatic lipomas and steatosis was demonstrated. Fifty percent of hepatic lipomas associated steatosis, while this association was present in only 9% of the non-lipomatous lesions.
CONCLUSION
Lipomas have a significantly greater association with steatosis when compared to nonlipomatous lesions. This relationship may be related to a common insuline resistance mechanism.
目的
确定肝脂肪瘤比其他良性肝病变更普遍存在肝脂肪变性。
材料与方法
对 92 例良性肝病变进行了磁共振成像（MR）分析。其中有 6 例脂肪瘤和 86 例非脂肪瘤性病变，包括 55 例肝血管瘤、23 例局灶性结节性增生（FNH）和 8 例腺瘤。所有研究均包括化学位移 T1 加权序列（同相位和反相位），以评估脂肪变性的存在。
结果
肝脂肪瘤与脂肪变性之间存在统计学显著关系（Fischer 精确检验，p=0.019）。50%的肝脂肪瘤伴有脂肪变性，而这种相关性在非脂肪瘤性病变中仅存在 9%。
结论
与非脂肪瘤性病变相比，脂肪瘤与脂肪变性的相关性显著更高。这种关系可能与共同的胰岛素抵抗机制有关。
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