Department of Neurology, Chushang Show-Chwan Hospital, No. 75, Sec. 2, Chi-Shang Road, Chushang Jenn, Nantou 557, Taiwan.
J Clin Neurosci. 2011 Sep;18(9):1266-8. doi: 10.1016/j.jocn.2011.01.021. Epub 2011 Jul 12.
The syndrome of acute bilateral basal ganglia (BG) lesions in patients with diabetic uremia normally affects Asian patients and usually presents with parkinsonian symptoms. We report two patients with this syndrome suffering from acute generalized choreic movements. The brain MRI of both patients revealed a cytotoxic-type of edema in the bilateral BG during the acute phase of the syndrome. After supportive treatment, they completely recovered from generalized chorea and the period of hyperkinesia corresponded to the acute exacerbation of the metabolic disturbance. Follow-up brain MRI revealed complete resolution of the abnormal signal. Thus, generalized chorea may be the initial presenting symptom of the syndrome and bilateral BG lesions probably originate from cytotoxic-type edema.
糖尿病尿毒症患者的急性双侧基底节（BG）综合征通常影响亚洲患者，并且通常表现为帕金森症状。我们报告了两例患有这种综合征的患者，他们患有急性全身性舞蹈病。这两名患者的脑部 MRI 在综合征的急性阶段显示双侧 BG 存在细胞毒性水肿。经过支持性治疗，他们完全从全身性舞蹈病中恢复过来，并且运动亢进期与代谢紊乱的急性加重相对应。随访脑 MRI 显示异常信号完全消退。因此，全身性舞蹈病可能是该综合征的初始表现症状，而双侧 BG 病变可能源于细胞毒性水肿。
