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Vaccine design reaches the atomic level.
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Rational design of a meningococcal antigen inducing broad protective immunity.
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Structure-based vaccines provide protection in a mouse model of ehrlichiosis.
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Design and characterization of epitope-scaffold immunogens that present the motavizumab epitope from respiratory syncytial virus.
J Mol Biol. 2011 Jun 24;409(5):853-66. doi: 10.1016/j.jmb.2011.04.044. Epub 2011 Apr 27.
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Structure of the uncomplexed Neisseria meningitidis factor H-binding protein fHbp (rLP2086).
Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 May 1;67(Pt 5):531-5. doi: 10.1107/S1744309111006154. Epub 2011 Apr 20.
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Elicitation of structure-specific antibodies by epitope scaffolds.
Proc Natl Acad Sci U S A. 2010 Oct 19;107(42):17880-7. doi: 10.1073/pnas.1004728107. Epub 2010 Sep 27.
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Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1.
Science. 2010 Aug 13;329(5993):856-61. doi: 10.1126/science.1187659. Epub 2010 Jul 8.
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Structural basis for broad and potent neutralization of HIV-1 by antibody VRC01.
Science. 2010 Aug 13;329(5993):811-7. doi: 10.1126/science.1192819. Epub 2010 Jul 8.
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Complement control protein factor H: the good, the bad, and the inadequate.
Mol Immunol. 2010 Aug;47(13):2187-97. doi: 10.1016/j.molimm.2010.05.007.
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Review of meningococcal group B vaccines.
Clin Infect Dis. 2010 Mar 1;50 Suppl 2(S2):S54-65. doi: 10.1086/648966.

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