Division of Nursing, Curry College, Milton, MA, USA.
Am J Nurs. 2009 Oct;109(10):50-7; quiz 58. doi: 10.1097/01.NAJ.0000361493.75589.06.
Pharmacogenomics is a rapidly growing field of research into the ways in which genetic variation affects drug response. Its objective is to develop precisely targeted, optimal drug therapy. One area of pharmacogenomics focuses on identifying genetic markers for differences in the way people metabolize drugs; another concentrates on developing genetic tests that predict how specific patients will respond to agents such as statins or cancer therapies. Nurses are now called upon to interpret such information or services in order to provide appropriate patient teaching regarding drug selection.
药物基因组学是一个快速发展的研究领域,旨在研究遗传变异如何影响药物反应。其目标是开发精确靶向、最佳的药物治疗方法。药物基因组学的一个研究领域集中在确定药物代谢方式存在差异的遗传标记上;另一个研究领域则集中在开发基因测试上,以预测特定患者对他汀类药物或癌症治疗等药物的反应。现在,护士需要解读这些信息或服务,以便为患者提供关于药物选择的适当教育。