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New side effect of the hypoxic cell sensitizer, misonidazole.

作者信息

Partington J, Koziol D, Chapman D, Rabin H, Urtasun R C

出版信息

Cancer Treat Rep. 1979 Jan;63(1):123-5.

PMID:217536
Abstract

As part of a phase II study with the hypoxic cell radiosensitizer, misonidazole, we have encountered two cases of dermatitis. When all drugs were withdrawn and the patients were challenged with a small single dose of misonidazole, identical adverse reactions reappeared demonstrating a drug-related skin hypersensitivity.

摘要

相似文献

1
New side effect of the hypoxic cell sensitizer, misonidazole.
Cancer Treat Rep. 1979 Jan;63(1):123-5.
2
Skin rashes associated with the administration of the 2-nitroimidazole, misonidazole.与2-硝基咪唑类药物米索硝唑给药相关的皮疹
Cancer Treat Rep. 1980 Feb-Mar;64(2-3):263-8.
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[Clinical trials of hypoxic cell sensitizer misonidazole].[乏氧细胞增敏剂米索硝唑的临床试验]
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Clinical experience with misonidazole: high dose fractions versus daily low doses.米索硝唑的临床经验:高剂量分次给药与每日低剂量给药对比
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[Clinical experiences with the radiosensitizer Misonidazol (author's transl)].放射增敏剂米索硝唑的临床经验(作者译)
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Clinical trials of misonidazole in the United States.
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引用本文的文献

1
A phase I study of misonidazole and pelvic irradiation in patients with carcinoma of cervix.一项关于米索硝唑与盆腔放疗用于宫颈癌患者的I期研究。
Br J Cancer. 1982 Jun;45(6):860-8. doi: 10.1038/bjc.1982.138.