Partington J, Koziol D, Chapman D, Rabin H, Urtasun R C
Cancer Treat Rep. 1979 Jan;63(1):123-5.
As part of a phase II study with the hypoxic cell radiosensitizer, misonidazole, we have encountered two cases of dermatitis. When all drugs were withdrawn and the patients were challenged with a small single dose of misonidazole, identical adverse reactions reappeared demonstrating a drug-related skin hypersensitivity.