• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

2-(2-{[(苄氧基)羰基]氨基}-丙烷-2-基)-5-羟基-6-氧代-1,6-二氢嘧啶-4-羧酸甲酯

Methyl 2-(2-{[(benz-yloxy)carbon-yl]amino}-propan-2-yl)-5-hy-droxy-6-oxo-1,6-dihydro-pyrimidine-4-carboxyl-ate.

作者信息

Shang Zhenhua, Ha Jing, Yu Yifeng, Zhao Xiaodan

机构信息

College of Chemical and Pharmaceutical Engineering, Hebei University of Science and Technology, Shijiazhuang 050018, People's Republic of China.

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2011 Jun 1;67(Pt 6):o1336. doi: 10.1107/S1600536811016278. Epub 2011 May 7.

DOI:10.1107/S1600536811016278
PMID:21754732
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3120555/
Abstract

In the title compound, C(17)H(19)N(3)O(6), the dihedral angle between the two aromatic rings is 45.9 (1)°. The crystal structure is stabilized through inter-molecular N-H⋯O hydrogen bonds and intra-molecular O-H⋯O hydrogen bonds are also present.

摘要

在标题化合物C₁₇H₁₉N₃O₆中，两个芳环之间的二面角为45.9（1）°。晶体结构通过分子间N-H⋯O氢键得以稳定，并且还存在分子内O-H⋯O氢键。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d74b/3120555/489fb232c8bf/e-67-o1336-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d74b/3120555/df92e1105692/e-67-o1336-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d74b/3120555/545c2e52f0eb/e-67-o1336-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d74b/3120555/489fb232c8bf/e-67-o1336-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d74b/3120555/df92e1105692/e-67-o1336-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d74b/3120555/545c2e52f0eb/e-67-o1336-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d74b/3120555/489fb232c8bf/e-67-o1336-fig3.jpg

相似文献

1
Methyl 2-(2-{[(benz-yloxy)carbon-yl]amino}-propan-2-yl)-5-hy-droxy-6-oxo-1,6-dihydro-pyrimidine-4-carboxyl-ate.2-(2-{[(苄氧基)羰基]氨基}-丙烷-2-基)-5-羟基-6-氧代-1,6-二氢嘧啶-4-羧酸甲酯
Acta Crystallogr Sect E Struct Rep Online. 2011 Jun 1;67(Pt 6):o1336. doi: 10.1107/S1600536811016278. Epub 2011 May 7.
2
Methyl 2-(2-{[(benz-yloxy)carbon-yl]amino}-propan-2-yl)-5-hy-droxy-6-meth-oxy-pyrimidine-4-carboxyl-ate.2-(2-{[(苄氧基)羰基]氨基}-丙烷-2-基)-5-羟基-6-甲氧基嘧啶-4-羧酸甲酯
Acta Crystallogr Sect E Struct Rep Online. 2011 Jun 1;67(Pt 6):o1335. doi: 10.1107/S160053681101628X. Epub 2011 May 7.
3
Crystal structures of the 1:1 salts of 2-amino-4-nitro-benzoate with each of (2-hy-droxy-eth-yl)di-methyl-aza-nium, -but-yl(2-hy-droxy-eth-yl)aza-nium and 1,3-dihy-droxy-2-(hy-droxy-meth-yl)propan-2-aminium.2-氨基-4-硝基苯甲酸盐与（2-羟乙基）二甲基氮鎓、丁基（2-羟乙基）氮鎓和1,3-二羟基-2-（羟甲基）丙烷-2-铵各自形成的1:1盐的晶体结构。
Acta Crystallogr E Crystallogr Commun. 2018 Nov 9;74(Pt 12):1735-1740. doi: 10.1107/S2056989018015578. eCollection 2018 Dec 1.
4
Methyl 2-[2-(benzyl-oxycarbon-ylamino)-propan-2-yl]-5-hy-droxy-1-methyl-6-oxo-1,6-dihydro-pyrimidine-4-carboxyl-ate.2-[2-(苄基-氧羰基氨基)-丙烷-2-基]-5-羟基-1-甲基-6-氧代-1,6-二氢嘧啶-4-羧酸甲酯
Acta Crystallogr Sect E Struct Rep Online. 2012 Nov 1;68(Pt 11):o3175. doi: 10.1107/S160053681204233X. Epub 2012 Oct 20.
5
Methyl 2-[2-(benzyl-oxycarbonyl-amino)-propan-2-yl]-5-hy-droxy-6-meth-oxy-pyrimidine-4-carboxyl-ate.2-[2-(苄氧羰基氨基)-2-丙基]-5-羟基-6-甲氧基嘧啶-4-羧酸甲酯
Acta Crystallogr Sect E Struct Rep Online. 2011 Jan 8;67(Pt 2):o274. doi: 10.1107/S160053681005467X.
6
4-{(4Z)-4-[(2Z)-3-(4-Fluoro-anilino)-1-hy-droxy-but-2-en-1-yl-idene]-3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl}-benzene-sulfonamide.4-{（4Z）-4-[(2Z)-3-(4-氟苯胺基)-1-羟基丁-2-烯-1-亚基]-3-甲基-5-氧代-4,5-二氢-1H-吡唑-1-基}-苯磺酰胺
Acta Crystallogr Sect E Struct Rep Online. 2012 Mar 1;68(Pt 3):o762-3. doi: 10.1107/S1600536812006502. Epub 2012 Feb 17.
7
rac-Ethyl 4-hy-droxy-6-(2-hy-droxy-phen-yl)-2-oxo-4-(trifluoro-methyl)per-hydro-pyrimidine-5-carboxyl-ate.外消旋-4-羟基-6-(2-羟基苯基)-2-氧代-4-(三氟甲基)全氢嘧啶-5-羧酸乙酯
Acta Crystallogr Sect E Struct Rep Online. 2010 Jun 16;66(Pt 7):o1651. doi: 10.1107/S1600536810021355.
8
Ethyl 4-hy-droxy-6-(4-hy-droxy-phen-yl)-4-trifluoro-methyl-2-sulfanyl-idene-1,3-diazinane-5-carboxyl-ate ethanol monosolvate.4-羟基-6-(4-羟基苯基)-4-三氟甲基-2-硫亚基-1,3-二嗪烷-5-羧酸乙酯乙醇单溶剂合物
Acta Crystallogr Sect E Struct Rep Online. 2011 May 1;67(Pt 5):o1280-1. doi: 10.1107/S1600536811015376. Epub 2011 Apr 29.
9
Dimethyl 4-(4-hy-droxy-phen-yl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxyl-ate.4-(4-羟基苯基)-2,6-二甲基-1,4-二氢吡啶-3,5-二甲酸二甲酯
Acta Crystallogr Sect E Struct Rep Online. 2011 Sep 1;67(Pt 9):o2362-3. doi: 10.1107/S1600536811032521. Epub 2011 Aug 17.
10
6-(2-Chloro-benz-yl)-1-(4-chloro-phen-yl)-7-hy-droxy-2,3-dihydro-1H-imidazo[1,2-a]pyrimidin-5-one.6-（2-氯苄基）-1-（4-氯苯基）-7-羟基-2,3-二氢-1H-咪唑并[1,2-a]嘧啶-5-酮
Acta Crystallogr Sect E Struct Rep Online. 2010 Oct 9;66(Pt 11):o2742-3. doi: 10.1107/S160053681003919X.

引用本文的文献

1
Raltegravir monohydrate.一水拉替拉韦
Acta Crystallogr Sect E Struct Rep Online. 2013 Nov 6;69(Pt 12):o1743-4. doi: 10.1107/S1600536813029747.
2
Methyl 2-[2-(benzyl-oxycarbon-ylamino)-propan-2-yl]-5-hy-droxy-1-methyl-6-oxo-1,6-dihydro-pyrimidine-4-carboxyl-ate.2-[2-(苄基-氧羰基氨基)-丙烷-2-基]-5-羟基-1-甲基-6-氧代-1,6-二氢嘧啶-4-羧酸甲酯
Acta Crystallogr Sect E Struct Rep Online. 2012 Nov 1;68(Pt 11):o3175. doi: 10.1107/S160053681204233X. Epub 2012 Oct 20.

本文引用的文献

1
6-Amino-2,5-bis-(pivaloylamino)pyrimidin-4(3H)-one dihydrate.
Acta Crystallogr Sect E Struct Rep Online. 2009 Jun 6;65(Pt 7):o1484-5. doi: 10.1107/S1600536809019461.
2
Raltegravir with optimized background therapy for resistant HIV-1 infection.拉替拉韦联合优化背景治疗用于耐药HIV-1感染
N Engl J Med. 2008 Jul 24;359(4):339-54. doi: 10.1056/NEJMoa0708975.
3
A short history of SHELX.SHELX简史。
Acta Crystallogr A. 2008 Jan;64(Pt 1):112-22. doi: 10.1107/S0108767307043930. Epub 2007 Dec 21.