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感染猫免疫缺陷病毒的实验性猫中淋巴细胞对有丝分裂原的增殖反应抑制

Suppression of lymphocyte blastogenesis to mitogens in cats experimentally infected with feline immunodeficiency virus.

作者信息

Lin D S, Bowman D D, Jacobson R H, Barr M C, Fevereiro M, Williams J R, Noronha F M, Scott F W, Avery R J

机构信息

Department of Microbiology, Immunology, and Parasitology, New York State College of Veterinary Medicine, Cornell University, Ithaca 14853-6401.

出版信息

Vet Immunol Immunopathol. 1990 Oct;26(2):183-9. doi: 10.1016/0165-2427(90)90066-2.

DOI:10.1016/0165-2427(90)90066-2
PMID:2175530
Abstract

Lymphocytes from normal cats or cats experimentally infected with feline immunodeficiency virus (FIV) were stimulated with phytohemagglutinin, pokeweed mitogen, or concanavalin A. Lymphocytes from infected cats had lower responses than those from uninfected cats. These results support the hypothesis that FIV induces immunosuppression.

摘要

用植物血凝素、商陆丝裂原或刀豆球蛋白A刺激来自正常猫或实验感染猫免疫缺陷病毒（FIV）的猫的淋巴细胞。感染猫的淋巴细胞反应低于未感染猫的淋巴细胞。这些结果支持FIV诱导免疫抑制的假说。

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引用本文的文献

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Some aspects of humoral and cellular immunity in naturally occuring feline infectious peritonitis.
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J Virol. 1993 Apr;67(4):2202-8. doi: 10.1128/JVI.67.4.2202-2208.1993.
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Localization of the viral antigen of feline immunodeficiency virus in the lymph nodes of cats at the early stage of infection.猫免疫缺陷病毒的病毒抗原在感染早期猫淋巴结中的定位。
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