Movement Disorders Unit, Neurology Service, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Mov Disord. 2011 Aug 15;26(10):1808-13. doi: 10.1002/mds.23359. Epub 2011 Jul 13.
A 56-year-old man presented with gait disturbance, personality change, and behavioral disturbances. He subsequently developed falls, postural instability, and axial rigidity. The cognitive problems progressed and he developed aphasia and later eye movement abnormalities. He died after 9 years of disease. Experts discuss the syndromal diagnosis and predict the underlying pathology. The pathological diagnosis is given and clinical learning points are considered.
一位 56 岁男性因步态障碍、性格改变和行为障碍就诊。随后他出现跌倒、姿势不稳和轴性僵硬。认知问题进展,他出现了失语症,随后出现眼球运动异常。他在患病 9 年后去世。专家讨论了综合征诊断并预测了潜在的病理学。给出了病理诊断,并考虑了临床学习要点。