Horpácsy G, Zinsmeyer J, Schröder K, Schnells G
Circ Shock. 1977;4(1):55-68.
The action of Trasylol on the lysosomal and ATP changes after renal-stalk clamping in rats was examined. It was found that, in the presence of an effective Trasylol concentration, a distinct stabilization of the lysosomal membrane can be detected after 30 min of renal-stalk clamping. It was also found that there is only an indirect relationship between lysosomal changes and ATP metabolism under the action of Trasylol. The more rapid regeneration of the ATP is a result of the better microcirculation. The results confirm the earlier belief that Trasylol acts primarily on the lysosomal membrane.
研究了抑肽酶对大鼠肾蒂钳夹后溶酶体及三磷酸腺苷（ATP）变化的作用。结果发现，在有效抑肽酶浓度存在的情况下，肾蒂钳夹30分钟后可检测到溶酶体膜有明显的稳定作用。还发现，在抑肽酶作用下，溶酶体变化与ATP代谢之间仅存在间接关系。ATP再生较快是微循环改善的结果。这些结果证实了早期的观点，即抑肽酶主要作用于溶酶体膜。
