Britton P D, Coulden R A
Department of Radiology, Addenbrooke's Hospital, Cambridge.
Clin Radiol. 1990 Dec;42(6):399-401. doi: 10.1016/s0009-9260(05)80892-x.
Duplex Doppler ultrasound was used to examine 50 breast lesions in 45 patients. Examination was confined to the region of interest, which in most cases was a palpable lump, and the corresponding area of the contralateral breast as a control. In only one patient was a Doppler signal obtained from a normal breast. Nine of the 50 lesions were believed to represent simple breast cysts at sonography and were not treated further. The remaining 41 lesions were excised; 22 were carcinomas and 19 benign (fibrocystic disease 7, fibroadenomas 5, miscellaneous 7). Doppler signals were obtained in 20 of the carcinomas and three of the benign lesions. In this series, the sensitivity of duplex Doppler ultrasound for the detection of breast carcinoma was 91%, and the specificity 89%. The positive predictive value was 87% and the negative predictive value 93%.
采用双功多普勒超声对45例患者的50个乳腺病变进行检查。检查局限于感兴趣区域，在大多数情况下为可触及的肿块，以及对侧乳腺的相应区域作为对照。仅1例患者从正常乳腺获得了多普勒信号。50个病变中9个在超声检查中被认为是单纯乳腺囊肿，未进一步治疗。其余41个病变被切除；22个为癌，19个为良性（纤维囊性疾病7个、纤维腺瘤5个、其他7个）。20个癌和3个良性病变获得了多普勒信号。在该系列中，双功多普勒超声检测乳腺癌的敏感性为91%，特异性为89%。阳性预测值为87%，阴性预测值为93%。
