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伊朗131碘-碘化钠治疗患者基于外照射剂量率和残余活度的出院标准。

Criteria for patient release according to external dose rate and residual activity in patients treated with 131I-sodium iodide in Iran.

作者信息

Ahmadi Jeshvaghane N, Paydar R, Fasaei B, Pakneyat A, Karamloo A, Deevband M R, Khosravi H R

机构信息

National Radiation Protection Department, Iranian Nuclear Regulatory Authority, PO Box 14155-4494, Tehran, Iran.

出版信息

Radiat Prot Dosimetry. 2011 Sep;147(1-2):264-6. doi: 10.1093/rpd/ncr305. Epub 2011 Jul 13.

DOI:10.1093/rpd/ncr305
PMID:21757441
Abstract

External dose rate (ED) and residual activity (RA) of patients treated with (131)I sodium iodide are two main factors, to consider before release of patients. In this study, six nuclear medicine centres out of total seven centres in Iran were selected and measurements have been done on 330 patients. ED of patients was measured by physicists of the centres for 6 months (May-November 2009) at a 1 m distance from the thyroid of each patient on the first, second and third days after administration by a calibrated survey meter. The maximum and minimum values of ED were 21 (SD = 18) and 11 (SD = 4) µSv h(-1), respectively. Furthermore, the maximum and minimum values of RA during release of patient were 720 and 250 MBq, respectively. According to the study, we recommend a release activity limit of 500 MBq (14 mCi) or a dose rate level of 20 µSv h(-1) at 1 m from the patient to be set instead of a release activity limit of 1100 MBq (30 mCi) as it is now for the country.

摘要

接受碘化钠(¹³¹I)治疗的患者的外照射剂量率(ED)和残留活度(RA)是患者出院前需要考虑的两个主要因素。在本研究中,从伊朗总共七个核医学中心中选取了六个中心,并对330名患者进行了测量。各中心的物理学家在给药后的第一天、第二天和第三天,使用校准过的辐射测量仪,在距离每位患者甲状腺1米处,对患者的外照射剂量率进行了为期6个月(2009年5月至11月)的测量。外照射剂量率的最大值和最小值分别为21(标准差 = 18)和11(标准差 = 4)微希沃特每小时(µSv h⁻¹)。此外,患者出院时残留活度的最大值和最小值分别为720和250兆贝可(MBq)。根据该研究,我们建议设定一个出院活度限制为500兆贝可(14毫居里),或在距离患者1米处剂量率水平为20微希沃特每小时(µSv h⁻¹),而不是该国目前设定的1100兆贝可(30毫居里)的出院活度限制。

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