Effects of EDD on p53 function are context-specific.
作者信息
Watts Colin K, Saunders Darren N
出版信息
J Biol Chem. 2011 Jul 15;286(28):le13; author reply le14. doi: 10.1074/jbc.L110.182527.
Abstract
摘要
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本文引用的文献
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EDD inhibits ATM-mediated phosphorylation of p53.EDD 抑制 ATM 介导的 p53 磷酸化。
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2
The E3 ubiquitin ligase EDD regulates S-phase and G(2)/M DNA damage checkpoints.E3泛素连接酶EDD调节S期和G(2)/M期DNA损伤检查点。
Cell Cycle. 2007 Dec 15;6(24):3070-7. doi: 10.4161/cc.6.24.5021. Epub 2007 Sep 7.
3
Edd, the murine hyperplastic disc gene, is essential for yolk sac vascularization and chorioallantoic fusion.Edd，即小鼠增生性椎间盘基因，对卵黄囊血管形成和绒毛膜尿囊融合至关重要。
Mol Cell Biol. 2004 Aug;24(16):7225-34. doi: 10.1128/MCB.24.16.7225-7234.2004.
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The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53.人乳头瘤病毒16型和18型编码的E6癌蛋白可促进p53的降解。
Cell. 1990 Dec 21;63(6):1129-36. doi: 10.1016/0092-8674(90)90409-8.
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