实验性先天性巨细胞病毒迷路炎和感音神经性听力损失

Experimental congenital cytomegalovirus labyrinthitis and sensorineural hearing loss.

作者信息

Woolf N K

机构信息

Department of Surgery, University of California Medical Center, San Diego 92161.

出版信息

Am J Otolaryngol. 1990 Sep-Oct;11(5):299-303. doi: 10.1016/0196-0709(90)90058-4.

DOI:10.1016/0196-0709(90)90058-4

PMID:2176063

Abstract

Cytomegalovirus is a leading cause of human congenital viral infection and hearing loss. The pathogenesis of human congenital cytomegalovirus infection is poorly understood. We have developed a reproducible model of congenital cytomegalovirus-induced sensorineural hearing loss in guinea pigs. This report reviews our previously published results and provides additional new information about this model.

摘要

巨细胞病毒是人类先天性病毒感染和听力丧失的主要原因。人类先天性巨细胞病毒感染的发病机制尚不清楚。我们已经建立了一种可重复的豚鼠先天性巨细胞病毒诱导的感音神经性听力损失模型。本报告回顾了我们之前发表的结果，并提供了有关该模型的更多新信息。