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在同一所医院,采用团队医疗模式,比较由风湿科医生和骨科医生治疗的类风湿关节炎患者的特征和治疗效果。

Comparison of characteristics and therapeutic efficacy in rheumatoid arthritis patients treated by rheumatologists and those treated by orthopedic surgeons under a team medicine approach at the same institute.

机构信息

Institute of Rheumatology, Tokyo Women's Medical University, 10-22 Kawada, Shinjuku, Tokyo 162-0054, Japan.

出版信息

Mod Rheumatol. 2012 Apr;22(2):209-15. doi: 10.1007/s10165-011-0495-7. Epub 2011 Jul 15.

Abstract

The treatment of rheumatoid arthritis (RA) has improved dramatically with the advent of the latest generation of disease-modifying antirheumatic drugs. Despite these advances, in some patients inflammation is not diminished sufficiently to prevent irreversible musculoskeletal damage, thereby necessitating surgical intervention to reduce pain and improve function. For RA treatment, Japanese orthopedic surgeons also prescribe medication. In this study, we examined whether this Japanese system is effective for RA treatment. We analyzed the clinical condition of RA patients treated by rheumatologists and those treated by orthopedists in a linked registry study using information from a large observational cohort of RA patients followed every half year from 2000 to 2010 (the IORRA cohort). Two groups of patients were compared: patients treated by rheumatologists (rheumatologic group) and patients treated by orthopedists (orthopedic group). The results revealed that patients in the orthopedic group were older, more likely to be female, and had a longer disease duration than patients in the rheumatologic group. The proportion of patients with a history of joint surgery was also much higher in the orthopedic group than in the rheumatologic group. The average scores on the Japanese version of the Health Assessment Questionnaire, and the remission ratio determined using a Boolean-based definition gradually increased from 2000 until 2010, and these findings were consistently better in the rheumatologic group than in the orthopedic group. These data suggest that patients treated primarily by orthopedists are more likely to have long-standing RA compared to patients treated by rheumatologists. Therefore, it is critical for rheumatologists and orthopedists to complement each other medically in the treatment of RA patients.

摘要

随着新一代疾病修饰抗风湿药物的出现,类风湿关节炎(RA)的治疗有了显著改善。尽管有了这些进展,但在某些患者中,炎症并没有减轻到足以防止不可逆转的肌肉骨骼损伤,因此需要手术干预来减轻疼痛和改善功能。对于 RA 的治疗,日本骨科医生也会开药物。在这项研究中,我们研究了日本的这种治疗体系对 RA 治疗是否有效。我们通过对从 2000 年至 2010 年每半年随访一次的大型 RA 患者观察队列的信息进行链接注册研究,分析了由风湿病医生和骨科医生治疗的 RA 患者的临床情况(IORRA 队列)。我们比较了两组患者:由风湿病医生治疗的患者(风湿性组)和由骨科医生治疗的患者(骨科组)。结果表明,骨科组的患者年龄较大,女性较多,且疾病持续时间较风湿性组长。骨科组的关节手术史患者比例也明显高于风湿性组。日本版健康评估问卷的平均得分和基于布尔定义的缓解率从 2000 年逐渐增加到 2010 年,并且在风湿性组中的这些发现始终优于骨科组。这些数据表明,与由风湿病医生治疗的患者相比,主要由骨科医生治疗的患者更有可能患有长期 RA。因此,风湿病医生和骨科医生在治疗 RA 患者时需要相互配合。

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