Zhang Chaofan, Liu Licheng, Wang Pengzhi, Liu Shanshan, Lin Wencheng, Hu Feng, Wu Weili, Chen Weijun, Cui Shangjin
Harbin Veterinary Research Institute of Chinese Academy of Agricultural Sciences, Harbin, Heilongjiang, China.
Virus Genes. 2011 Dec;43(3):342-9. doi: 10.1007/s11262-011-0642-4. Epub 2011 Jul 15.
We report a novel reovirus (MRV-HLJ/2007) isolated from swine in Heilongjiang Province, China. Genome sequence analysis indicated a close genetic relationship between MRV-HLJ/2007 and strain SC-A, which was isolated from swine in 2006 in Sichuan, China. Although phylogenetic analysis indicated that MRV-HLJ/2007 may have originated from the SC-A strain, the M2 and S3 genes differ between these strains. Phylogenetic analysis also showed that, except for differences in the S1 gene, MRV-HLJ/2007 and SC-A are closely related to a reovirus that infects humans. These findings suggest that MRV-HLJ/2007 might be a novel reovirus strain circulating in China.
我们报道了一种从中国黑龙江省猪体内分离出的新型呼肠孤病毒（MRV-HLJ/2007）。基因组序列分析表明，MRV-HLJ/2007与2006年在中国四川省猪体内分离出的SC-A毒株存在密切的遗传关系。尽管系统发育分析表明MRV-HLJ/2007可能起源于SC-A毒株，但这些毒株之间的M2和S3基因存在差异。系统发育分析还显示，除了S1基因存在差异外，MRV-HLJ/2007和SC-A与一种感染人类的呼肠孤病毒密切相关。这些发现表明，MRV-HLJ/2007可能是在中国流行的一种新型呼肠孤病毒毒株。
