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[射频消融与聚焦超声治疗常年性变应性鼻炎的临床观察与比较]

[Clinical observation and comparison on radiofrequency ablation and focused ultrasound in treatment of perennial allergic rhinitis].

作者信息

Han Jibo, Kong Yonggang, Xu Yu, Tao Zezhang, Wang Yan

机构信息

Department of Otolaryngology Head and Neck Surgery, Renmin Hospital of Wuhan University, Wuhan, 430060, China.

出版信息

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2011 Apr;25(8):349-51.

Abstract

OBJECTIVE

To compare the therapeutic effect of radiofrequency ablation and focused ultrasound in treatment of allergic rhinitis which was refractory to medical therapy, and to explore the reliable and safe surgical treatment.

METHOD

Eighty-six perennial allergic rhinitis patients were divided randomly into two group. The radiofrequency ablation group included 40 patients and focused ultrasound group included 46 patients. A standard 0 to 10 visual analog scale (VAS) was used to assess the allergic symptoms therapeutic effect before and one year after treatment.

RESULT

Allergic symptoms were improved in both two groups one year after treatment. The total VAS score in radiofrequency ablation group decreased from 31.35 +/- 6.16 to 14.16 +/- 4.83 and the total effective power of this group was 87.5% at the twelfth month after surgical. While the total VAS score in focused ultrasound group decreased from 32.86 +/- 5.45 to 21.91 +/- 8.58 and total effective power was 69.6% (all P < 0.01).

CONCLUSION

This study had demonstrated that the radiofrequency ablation and focused ultrasound appears to be an effective and safe tool for treating allergic rhinitis which was refractory to medical therapy. Compared to focused ultrasound, the radiofrequency ablation seemed to have a longer time therapeutical effect. While the focused ultrasound was more safe and little trauma, which made it possible to the repeated application.

摘要

目的

比较射频消融术与聚焦超声治疗药物治疗无效的变应性鼻炎的疗效,探讨可靠且安全的手术治疗方法。

方法

将86例常年性变应性鼻炎患者随机分为两组。射频消融组40例,聚焦超声组46例。采用标准的0至10视觉模拟量表(VAS)评估治疗前及治疗后1年变应性症状的治疗效果。

结果

两组患者治疗1年后变应性症状均有改善。射频消融组VAS总分从31.35±6.16降至14.16±4.83,术后12个月该组总有效率为87.5%。而聚焦超声组VAS总分从32.86±5.45降至21.91±8.58,总有效率为69.6%(均P<0.01)。

结论

本研究表明,射频消融术和聚焦超声似乎是治疗药物治疗无效的变应性鼻炎的有效且安全的方法。与聚焦超声相比,射频消融术的治疗效果似乎持续时间更长。而聚焦超声更安全且创伤小,使其有可能重复应用。

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