Lin Hsin-Ching, Lin Pei-Wen, Friedman Michael, Chang Hsueh-Wen, Su Yan-Ye, Chen Yu-Jen, Pulver Tanya M
Department of Otolaryngology, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Arch Otolaryngol Head Neck Surg. 2010 Sep;136(9):892-5. doi: 10.1001/archoto.2010.135. Epub 2010 Jul 19.
To study the long-term outcomes of radiofrequency (RF) turbinate surgery for the treatment of allergic rhinitis refractory to medical therapy.
A retrospective review of a prospective data set.
Tertiary referral center.
A total of 146 patients with allergic rhinitis refractory to medical therapy undergoing RF turbinoplasty were included.
A standard 0 to 10 visual analog scale (VAS) was used to assess the allergic symptoms including nasal obstruction, rhinorrhea, sneezing, itchy nose, and itchy eyes prior to RF turbinoplasty and at 6 months and 5 years postoperatively. The long-term clinical benefits and complications were reviewed. Statistical analysis was determined by repeated measures of analysis of variance.
No adverse reactions such as bleeding, infection, adhesions, or olfactory change were encountered. Of the 146 patients, 119 were followed up at least 5 years postoperatively. Five years after treatment, 101 patients had complete data available for analysis. They reported improvement of nasal obstruction, with the mean (SD) VAS score decreasing from 6.65 (1.92) to 4.45 (2.54). The mean (SD) VAS score changed from 5.90 (2.79) to 3.79 (2.97) for rhinorrhea; from 5.15 (2.77) to 3.50 (2.77) for sneezing; from 3.67 (3.03) to 2.41 (2.30) for itchy nose; and from 2.94 (3.02) to 2.02 (2.42) for itchy eyes (all P < .001, paired t test with Bonferroni correction).
This long-term study has demonstrated that the RF turbinoplasty for allergic rhinitis appears to be an effective and safe tool for treating allergic rhinitis refractory to medical therapy.
研究射频鼻甲手术治疗药物治疗无效的变应性鼻炎的长期疗效。
对前瞻性数据集进行回顾性分析。
三级转诊中心。
共纳入146例药物治疗无效的变应性鼻炎患者,接受射频鼻甲成形术。
采用标准的0至10视觉模拟量表(VAS)评估射频鼻甲成形术前、术后6个月和5年时的变应性症状,包括鼻塞、流涕、打喷嚏、鼻痒和眼痒。回顾长期临床疗效和并发症。采用重复测量方差分析进行统计学分析。
未出现出血、感染、粘连或嗅觉改变等不良反应。146例患者中,119例术后至少随访5年。治疗5年后,101例患者有完整数据可供分析。他们报告鼻塞症状改善,平均(标准差)VAS评分从6.65(1.92)降至4.45(2.54)。流涕的平均(标准差)VAS评分从5.90(2.79)变为3.79(2.97);打喷嚏从5.15(2.77)变为3.50(2.77);鼻痒从3.67(3.03)变为2.41(2.30);眼痒从2.94(3.02)变为2.02(2.42)(所有P <.001,采用Bonferroni校正的配对t检验)。
这项长期研究表明,射频鼻甲成形术治疗变应性鼻炎似乎是治疗药物治疗无效的变应性鼻炎的一种有效且安全的方法。