Kaufmann Liane, Wood Guilherme, Rubinsten Orly, Henik Avishai
Institute of Applied Psychology, University for Health Sciences, Medical Informatics and Technology, Hall in Tyrol, Austria.
Dev Neuropsychol. 2011;36(6):763-87. doi: 10.1080/87565641.2010.549884.
The main aim of the present coordinate-based meta-analysis is to identify brain regions that are commonly activated in functional magnetic resonance imaging studies (fMRI) investigating number processing and calculation in children. Here, we include 19 developmental fMRI papers, five of which also examine children diagnosed with developmental dyscalculia and/or mathematical disability. Results reveal that children produce consistent fronto-parietal activation patterns in response to number processing and calculation. Importantly, activation patterns are clearly modulated by notation, task complexity, and competence level. Activation differences between children with and without dyscalculia are observable in number-relevant parietal regions as well as in (pre)frontal and occipital cortex.
当前基于坐标的元分析的主要目的是确定在功能磁共振成像（fMRI）研究中，儿童在进行数字处理和计算时共同激活的脑区。在此，我们纳入了19篇发育性fMRI论文，其中5篇还研究了被诊断为发育性计算障碍和/或数学障碍的儿童。结果显示，儿童在进行数字处理和计算时会产生一致的额顶叶激活模式。重要的是，激活模式明显受到符号表示、任务复杂性和能力水平的调节。在与数字相关的顶叶区域以及（前）额叶和枕叶皮质中，可以观察到有计算障碍和无计算障碍儿童之间的激活差异。
