Morita S, Sonoyama T, Nishiyama K, Nakagi K, Nomi S, Ohmori Y, Oka T, Fukuda S
Dept. of Surgery, Kyoto Prefectural Yosanoumi Hospital.
Gan No Rinsho. 1990 Dec;36(15):2599-604.
Two cases of a pelvic evisceration have been performed, due to an irradiation-induced rectal cancer. Described are the cases of two women who had been treated with irradiation for a cervical cancer following a hysterectomy, one patient being 65 years old and the other 67. After a latent period that lasted for 12 and 24 years, respectively, each had developed a rectal cancer. In each case, case excised specimen showed diffuse fibrosis and a hyaline change, reflecting the effect of radiation on the tumoral tissue. Cases of an irradiation-induced rectal cancer are uncommon, and the symptoms of enterocolitis caused by irradiation are similar to those of a colorectal cancer. The authors therefore suggest careful and long-term follow-up of patients that have received pelvic radiation.