Wang Yeming, Chen Jingyu
Department of General Thoracic Surgery, Wuxi People's Hospital Affiliated to Nanjing Medical University, Wuxi 214023, China.
Zhongguo Fei Ai Za Zhi. 2011 Jul;14(7):633-6. doi: 10.3779/j.issn.1009-3419.2011.07.14.
Lung carcinoma is a relative contraindication for lung transplantation (LTx). The improvement of this procedure may successfully treat novel end-stage pulmonary diseases. In the present study, we reported one case of bilateral LTx (BLT) in a young man with bilateral lung carcinoma and reviewed related literature to investigate patient selection and curative effect.
A 42-year-old male patient underwent BLT on October 21, 2010 in our hospital. Preoperative chest CT and PET-CT showed bilateral multiple nodules and mass without positive lymph nodes or extrapulmonary metastasis. Bronchioloalveolar carcinoma was identified histologically (T4N0M0, stage IIIb).
Routine therapies were performed postoperatively. The patient was discharged on post-operative day 66. There was no clinical or radiologic evidence of the recurrence of lung carcinoma in his latest follow-up of 6 months postoperatively.
LTx may be proposed as an efficient therapeutic option in selected patients of lung carcinoma.
肺癌是肺移植（LTx）的相对禁忌证。该手术的改进可能成功治疗新型终末期肺部疾病。在本研究中，我们报告了一例患有双侧肺癌的年轻男性接受双侧肺移植（BLT）的病例，并回顾相关文献以研究患者选择和疗效。
一名42岁男性患者于2010年10月21日在我院接受了双侧肺移植。术前胸部CT和PET-CT显示双侧多发结节及肿块，无阳性淋巴结或肺外转移。组织学诊断为细支气管肺泡癌（T4N0M0，Ⅲb期）。
术后进行了常规治疗。患者于术后第66天出院。在术后6个月的最新随访中，没有临床或影像学证据表明肺癌复发。
对于选定的肺癌患者，肺移植可作为一种有效的治疗选择。
