Department of Pediatric Surgery, Taizhou Hospital, Zhejiang Province, China.
J Pediatr Surg. 2011 Jul;46(7):E1-4. doi: 10.1016/j.jpedsurg.2011.03.011.
Inflammatory myofibroblastic tumor is a rare benign neoplasm. It is common in children and has been reported in various locations throughout the body but rarely in the rectum. A 13-month-old girl presented with a short history of a painless anal mass and no hematochezia. The mass was completely excised, and histologic examination of the initial biopsy showed fascicles of spindle cells in a mixed inflammatory background with predominance of plasma cells, typical of an inflammatory pseudotumor. The spindle cells were positive for smooth muscle actin and anaplastic lymphoma kinase staining. There is no evidence of recurrence or metastasis after a follow-up of 4.5 years.
炎性肌纤维母细胞瘤是一种罕见的良性肿瘤。它常见于儿童，可发生于身体的各个部位，但在直肠中很少见。一名 13 个月大的女孩出现了无痛性肛门肿块的短暂病史，没有血便。肿块被完全切除，初次活检的组织学检查显示在混合炎症背景中有梭形细胞束，以浆细胞为主，典型的炎性假瘤。梭形细胞对平滑肌肌动蛋白和间变性淋巴瘤激酶染色呈阳性。随访 4.5 年后，没有复发或转移的证据。
