成群的非典型 Spitz 肿瘤：唐氏综合征患儿的大鼻部病变。
Agminated atypical Spitz tumor: large nasal lesion in a child with Down syndrome.
机构信息
Department of Plastic and Oral Surgery, Children's Hospital Boston, Harvard Medical School, Boston, MA 02115, USA.
出版信息
J Pediatr Surg. 2011 Jul;46(7):1435-7. doi: 10.1016/j.jpedsurg.2011.03.002.
Abstract
We present a 5-year-old girl with Down syndrome and a 2.5-cm agminated atypical Spitz tumor of the nose. Although atypical Spitz tumor has uncertain malignant potential, trisomy 21 is protective against melanoma. This is the first description of an atypical Spitz tumor in a patient with Down syndrome and the largest nasal lesion reported.
摘要
我们报告了一例患有唐氏综合征的 5 岁女孩，其鼻部有 2.5 厘米的聚集性非典型 Spitz 肿瘤。虽然非典型 Spitz 肿瘤具有不确定的恶性潜能，但 21 三体对黑色素瘤有保护作用。这是首例唐氏综合征患者罹患非典型 Spitz 肿瘤的描述，也是报道的最大鼻部病变。
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