Division of Neurosurgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.
Pediatr Neurol. 2011 Aug;45(2):135-7. doi: 10.1016/j.pediatrneurol.2011.04.001.
We describe a rare case of desmoplastic infantile ganglioglioma that appears to have transformed into a glioblastoma multiforme tumor in a 5-year-old girl. The patient was initially treated with total removal of the tumor, without subsequent radiation therapy or chemotherapy. She was in good health for 3 years, but manifested a sudden onset of seizures, followed by severe headache, vomiting, and left-sided weakness. Cranial magnetic resonance imaging revealed a large mass with rim enhancement at the previously operated site. The mass was completely removed, and the pathology report revealed glioblastoma multiforme. Postoperative chemotherapy and radiation treatment were administered. She has been followed for 11 years, and is alive without recurrence.
我们描述了一例罕见的促纤维增生性婴儿型神经节胶质瘤病例，该病例似乎在一名 5 岁女孩中转化为多形性胶质母细胞瘤。患者最初接受了肿瘤的完全切除，未接受后续的放疗或化疗。她在 3 年内身体状况良好，但突然出现癫痫发作，随后出现严重头痛、呕吐和左侧无力。头颅磁共振成像显示在先前手术部位有一个带有边缘增强的大肿块。肿块被完全切除，病理报告显示为多形性胶质母细胞瘤。术后给予化疗和放疗。她已经随访了 11 年，没有复发，仍存活。
