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[(110m)Ag]纳米颗粒的合成与表征及其在水生生物全身放射自显影中的应用

Synthesis and characterization of [(110m)Ag]-nanoparticles with application to whole-body autoradiography of aquatic organisms.

作者信息

Al-Sid-Cheikh Maya, Pelletier Emilien, Rouleau Claude

机构信息

Institut des Sciences de la Mer de Rimouski (ISMER), Université du Québec à Rimouski, 310 allée des Ursulines, Rimouski, Québec, Canada.

出版信息

Appl Radiat Isot. 2011 Oct;69(10):1415-21. doi: 10.1016/j.apradiso.2011.06.017. Epub 2011 Jul 6.

DOI:10.1016/j.apradiso.2011.06.017
PMID:21764324
Abstract

Silver nanoparticles (AgNp) were synthesized using aqueous solution of silver nitrate ([(110m)Ag]NO₃) with poly(allylamine) as a reducing agent and a stabilizer of the AgNp suspension. Nanoparticles were characterized by absorption spectroscopy, particle size analysis, atomic force microscopy (AFM), and transmission (TEM) electron microscopy. Different size nanoparticles (10-30 nm and 70-90 nm) were obtained by varying the polymer concentration and reaction time. The application of [(110m)Ag]AgNP to environmental studies, using nuclear techniques such as in vivo gamma counting and whole-body autoradiography, is demonstrated and discussed.

摘要

使用硝酸银水溶液([(110m)Ag]NO₃),以聚烯丙胺作为还原剂和银纳米颗粒(AgNp)悬浮液的稳定剂来合成银纳米颗粒。通过吸收光谱、粒度分析、原子力显微镜(AFM)和透射电子显微镜(TEM)对纳米颗粒进行表征。通过改变聚合物浓度和反应时间获得了不同尺寸的纳米颗粒(10 - 30纳米和70 - 90纳米)。展示并讨论了[(110m)Ag]AgNP在环境研究中的应用,采用了诸如体内γ计数和全身放射自显影等核技术。

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