Tambakis Charalambos L, Papadopoulos George, Sergentanis Theodoros N, Lagos Nikolaos, Arnaoutoglou Eleni, Labropoulos Nicos, Matsagkas Miltiadis I
Department of Surgery, University of Ioannina, Ioannina, Greece.
Vascular. 2011 Aug;19(4):187-94. doi: 10.1258/vasc.2010.oa0277. Epub 2011 Jul 15.
The purpose of this work is to investigate the correlation between regional oxygen saturation (rSO(2)) changes and stump pressure (SP) during cross-clamping of the internal carotid artery in carotid endarterectomy (CEA) and verify the perspectives of rSO(2) to become a criterion for shunting. Sixty consecutive CEAs under general anesthesia were studied prospectively. Selective shunting was based on SP ≤40 mmHg exclusively. Regression analysis with high order terms and receiver operating characteristic analysis were performed to investigate the association between ΔrSO(2)(%) and SP and to determine an optimal ΔrSO(2)(%) threshold for shunt insertion. A quadratic association between ΔrSO(2)(%) and SP was documented regarding the baseline to one and five minutes after cross-clamping intervals. A cut-off of 21 and 10.1% reduction from the baseline recording was identified as optimal for the distinction between patients needed or not a shunt regarding the first and fifth minute after cross-clamping, respectively. In conclusion, cerebral oximety reflects sufficiently cerebral oxygenation during CEA compared with SP, providing a useful mean for cerebral monitoring.
这项工作的目的是研究颈动脉内膜切除术(CEA)中颈内动脉交叉钳夹期间局部血氧饱和度(rSO₂)变化与残端压力(SP)之间的相关性,并验证rSO₂作为分流标准的前景。前瞻性研究了连续60例全身麻醉下的CEA。仅根据SP≤40 mmHg进行选择性分流。进行了高阶项回归分析和受试者工作特征分析,以研究ΔrSO₂(%)与SP之间的关联,并确定分流插入的最佳ΔrSO₂(%)阈值。记录了交叉钳夹间隔后1分钟和5分钟内,从基线开始的ΔrSO₂(%)与SP之间的二次关联。对于交叉钳夹后第1分钟和第5分钟,分别从基线记录降低21%和10.1%被确定为区分需要或不需要分流患者的最佳截断值。总之,与SP相比,脑血氧饱和度在CEA期间能充分反映脑氧合情况,为脑监测提供了一种有用的手段。