Athanasiu P, Petrescu A, Predescu E, Anghelescu S, Popa D P, Dumitrescu A M, Macarie I, Cristea C, Mihail V
Institut de Virologie Stefan S. Nicolau, Bucarest, Roumanie.
Rev Roum Virol. 1990 Apr-Jun;41(2):87-91.
Repeated intranasal administrations of NIVGRIP, influenza inactivated vaccine, to patients with chronic recurrent keratoconjunctivitis, led to a significant reduction of respiratory virus incidence, as revealed by the immunofluorescence test in the conjunctive epithelial cells. The effect is probably due to endogenous interferon stimulation by the vaccine, at the nasopharyngeal level.
对慢性复发性角结膜炎患者反复经鼻给予流感灭活疫苗NIVGRIP,免疫荧光试验显示结膜上皮细胞中呼吸道病毒发生率显著降低。这种效果可能是由于疫苗在鼻咽部水平对内源性干扰素的刺激所致。