[周期性疾病患者血液中白三烯B4和C4的水平]
[Level of leukotrienes B4 and C4 in the blood of patients with periodic disease].
作者信息
Gabrielian E S, Grigorian S V, Davtian D G, Mkhitarian G S, Panosian A G
出版信息
Biull Eksp Biol Med. 1990 Sep;110(9):296-7.
The level of LTB4 and LTC4 in blood plasma of patients with familial mediterranean fever is significantly higher than in healthy donors: 53 + 10 pg/ml for LTB4 (normal - 25 + 5 pg/ml) and 175 + 22 pg/ml for LTC4 (normal 67 + 19 pg/ml). The more increase of the LTB4 and LTC4 content in plasma is observed during attacks of fever - 107 + 21 pg/ml (LTB4) and 249 + 34 pg/ml (LTC4). Hyperbaric oxygenation of patients, used to relieve pain and fever, reduces the level of leukotrienes.
家族性地中海热患者血浆中白三烯B4（LTB4）和白三烯C4（LTC4）的水平显著高于健康供体：LTB4为53 + 10 pg/ml（正常为25 + 5 pg/ml），LTC4为175 + 22 pg/ml（正常为67 + 19 pg/ml）。在发热发作期间，血浆中LTB4和LTC4含量的升高更为明显——LTB4为107 + 21 pg/ml，LTC4为249 + 34 pg/ml。用于缓解疼痛和发热的患者高压氧疗可降低白三烯水平。
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