细胞治疗和卫星中心：心血管细胞治疗研究网络的经验。
Cell therapy and satellite centers: the Cardiovascular Cell Therapy Research Network experience.
机构信息
University of Texas School of Public Health, Houston, TX 77030, USA.
出版信息
Contemp Clin Trials. 2011 Nov;32(6):841-7. doi: 10.1016/j.cct.2011.07.001. Epub 2011 Jul 8.
Abstract
Due to the changing population in patients with myocardial infarction, recruiting patients in clinical trials continues to challenge clinical investigators. The Cardiovascular Cell Therapy Research Network (CCTRN) chose to expand the reach and power of its recruitment effort by incorporating both referral and treatment satellite centers. Eight treatment satellites were successfully identified and they screened patients over a two year period. The result of this effort was an increase in recruitment, with these treatment satellites contributing 30% of the patients to two of the three Network studies. The hurdles that these satellite treatment centers faced and how they surmounted them provide instruction to clinical research groups eager to expand to satellite systems and to health care practitioners who are interested in taking part in multicenter clinical trials.
摘要
由于心肌梗死患者的人口变化，临床试验的患者招募工作不断给临床研究人员带来挑战。心血管细胞治疗研究网络（CCTRN）选择通过纳入转诊和治疗卫星中心来扩大其招募工作的范围和影响力。成功确定了 8 个治疗卫星中心，它们在两年的时间里筛选了患者。这一努力的结果是招募人数的增加，这些治疗卫星中心为三个网络研究中的两个贡献了 30%的患者。这些卫星治疗中心所面临的障碍以及它们是如何克服这些障碍的，为渴望扩展到卫星系统的临床研究小组以及有兴趣参与多中心临床试验的医疗保健从业者提供了指导。
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