Rostotskaia V I, Vikhert T M, Khukhlaeva E A, Panina T, Namsaraeva G T
Zh Vopr Neirokhir Im N N Burdenko. 1990 Sep-Oct(5):6-8.
The late term results of surgical treatment of cerebellar astrocytomas in children are compared with the specific features of the histological structure of the tumor and the volume of the surgical intervention. The authors distinguish the prognostically unfavourable characteristics of the histological structure of cerebellar astrocytomas (mitotic figures, even occasional, polymorphism of cells or nuclei, combination of dense cellularity with proliferation of endothelium in the vessels) which determine the prognosis in total or subtotal removal of the tumor. The index "volume of operation" acquires highest prognostic significance in subtotal removal of the tumor. A recurrent tumor develops in all cases after subtotal removal, irrespective of the histological structure.
对儿童小脑星形细胞瘤手术治疗的远期结果与肿瘤组织学结构的特定特征及手术干预范围进行了比较。作者区分了小脑星形细胞瘤组织学结构中预后不良的特征(有丝分裂象,即使偶尔出现、细胞或细胞核的多形性、密集细胞性与血管内皮细胞增殖的组合),这些特征决定了肿瘤全切或次全切的预后。“手术范围”指标在肿瘤次全切中具有最高的预后意义。无论组织学结构如何,次全切后所有病例都会出现复发性肿瘤。