Ultrasound Department, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Ultrasound Med Biol. 2011 Sep;37(9):1436-43. doi: 10.1016/j.ultrasmedbio.2011.05.022. Epub 2011 Jul 20.
The aim of this study was to determine the appearance of breast lesions using acoustic radiation force impulse imaging (ARFI) and to correlate the ARFI values with the pathologic results. The area ratio (AR) and virtual touch tissue quantification (VTQ) values were analyzed in 86 patients (mean age 45.6 years, range 17-78 years) with 92 breast lesions (65 benign, 27 malignant; mean size 25.7 mm). The diagnostic performance of ultrasound (US) alone and US plus ARFI values were compared with respect to sensitivity, specificity and area under the curve (AUC) using a receiver operating characteristic curve analysis. The mean AR of the benign lesions (1.08 ± 0.21) differed from that of the malignant lesions (1.99 ± 0.63; p < 0.0001), as did the mean VTQ values (3.25 ± 2.03 m/s vs. 8.22 ± 1.27 m/s; p < 0.0001). In conclusion, ARFI provides quantitative elasticity measurements, which may complement B-mode US and potentially improve the characterization of breast lesions.
本研究旨在通过声辐射力脉冲成像（ARFI）确定乳腺病变的外观，并将 ARFI 值与病理结果相关联。对 86 例患者（平均年龄 45.6 岁，范围 17-78 岁）的 92 个乳腺病变（65 个良性，27 个恶性；平均大小 25.7mm）进行了面积比（AR）和虚拟触摸组织量化（VTQ）值分析。采用受试者工作特征曲线分析比较了超声（US）单独和 US 加 ARFI 值的诊断性能，比较了灵敏度、特异性和曲线下面积（AUC）。良性病变的平均 AR（1.08±0.21）与恶性病变的平均 AR（1.99±0.63）不同（p<0.0001），平均 VTQ 值也不同（3.25±2.03m/s 与 8.22±1.27m/s；p<0.0001）。总之，ARFI 提供了定量弹性测量，这可能补充 B 型超声并有可能改善乳腺病变的特征化。
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