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僵人综合征与妊娠。

Stiff person syndrome and pregnancy.

机构信息

From St. Louis University School of Medicine, St. Louis, Missouri; and the Department of Obstetrics and Gynecology and Women's Health Division of Maternal-Fetal Medicine, St. Mary's Health Center, St. Louis, Missouri.

出版信息

Obstet Gynecol. 2011 Aug;118(2 Pt 2):454-457. doi: 10.1097/AOG.0b013e318216196b.

Abstract

BACKGROUND

Stiff person syndrome, also known as Moersche-Woltman syndrome, is a debilitating disorder that is rarely seen in the pregnant patient. It is characterized by muscle spasms triggered by startle, voluntary movement, or tactile or emotional stimuli, occurring predominantly in the axial musculature.

CASE

A woman diagnosed with stiff person syndrome became pregnant 2 months after her diagnosis. Her medication regimen was adjusted because of pregnancy, and anesthesia was initiated early in labor to control her pain. She was able to have a full-term pregnancy with few complications.

CONCLUSION

Stiff person syndrome may be successfully managed in pregnancy. Patients can deliver vaginally with adequate pain control to avoid muscle spasms.

摘要

背景

僵人综合征,也称为莫尔施-沃尔夫曼综合征,是一种罕见于孕妇的使人虚弱的疾病。其特征是由惊吓、主动运动或触觉或情绪刺激引发的肌肉痉挛,主要发生在轴性肌肉中。

病例

一位被诊断患有僵人综合征的女性在确诊后 2 个月怀孕。由于怀孕,她的药物治疗方案进行了调整,分娩早期开始使用麻醉来控制疼痛。她成功地足月分娩,并发症很少。

结论

僵人综合征在妊娠期间可以得到成功的治疗。患者可以通过充分的疼痛控制进行阴道分娩,以避免肌肉痉挛。

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