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Parkinson disease: Poor results for retinal cell transplants in Parkinson disease.

作者信息

Cenci M Angela, Widner Håkan

出版信息

Nat Rev Neurol. 2011 Jul 19;7(8):424-5. doi: 10.1038/nrneurol.2011.111.

DOI:10.1038/nrneurol.2011.111
PMID:21769124
Abstract
摘要

相似文献

1
Parkinson disease: Poor results for retinal cell transplants in Parkinson disease.帕金森病：帕金森病视网膜细胞移植效果不佳。
Nat Rev Neurol. 2011 Jul 19;7(8):424-5. doi: 10.1038/nrneurol.2011.111.
2
Efficacy and safety of computer-assisted stereotactic transplantation of human retinal pigment epithelium cells in the treatment of Parkinson disease.计算机辅助立体定向移植人视网膜色素上皮细胞治疗帕金森病的疗效与安全性
J Comput Assist Tomogr. 2013 May-Jun;37(3):333-7. doi: 10.1097/RCT.0b013e318287367f.
3
[Cell transplantation study with German patients. Can retinal cells save the Parkinson brain?].[针对德国患者的细胞移植研究。视网膜细胞能拯救帕金森患者的大脑吗？]
MMW Fortschr Med. 2004 Jan 15;146(1-2):9.
4
Cell therapy for Parkinson's disease: have the glory days gone?帕金森病的细胞治疗：辉煌岁月已逝？
Lancet Neurol. 2011 Jun;10(6):492-3. doi: 10.1016/S1474-4422(11)70101-6. Epub 2011 May 10.
5
Modulation of Abnormal Metabolic Brain Networks by Experimental Therapies in a Nonhuman Primate Model of Parkinson Disease: An Application to Human Retinal Pigment Epithelial Cell Implantation.帕金森病非人灵长类动物模型中实验性疗法对异常代谢脑网络的调节作用：人类视网膜色素上皮细胞植入的应用。
J Nucl Med. 2016 Oct;57(10):1591-1598. doi: 10.2967/jnumed.115.161513. Epub 2016 Apr 7.
6
Embryonic stem cell implantation for the treatment of Stargardt’s disease and macular degeneration.胚胎干细胞植入治疗斯塔加特病和黄斑变性。
Regen Med. 2011 Sep;6(5):539-40. doi: 10.2217/rme.11.61.
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Science to practice: Cellular therapy of Parkinson disease--a new radiotracer to target transplanted dopaminergic cells with PET.从科学到实践：帕金森病的细胞治疗——一种新的放射性示踪剂，用于通过 PET 靶向移植的多巴胺能细胞。
Radiology. 2014 Jul;272(1):1-3. doi: 10.1148/radiol.14140548.
8
A reply to human retinal pigment epithelium (RPE) transplantation: outcome after autologous RPE-choroid sheet and RPE cell-suspension in a randomised clinical study.对人视网膜色素上皮（RPE）移植的回应：一项随机临床研究中自体RPE-脉络膜片和RPE细胞悬液移植后的结果
Br J Ophthalmol. 2011 Mar;95(3):431; author reply 431. doi: 10.1136/bjo.2010.191882. Epub 2010 Oct 26.
9
Neonatal human retinal pigment epithelial cells secrete limited trophic factors in vitro and in vivo following striatal implantation in parkinsonian rats.新生人类视网膜色素上皮细胞在体外分泌有限的营养因子，在帕金森病大鼠纹状体植入后在体内也分泌有限的营养因子。
J Neural Transm (Vienna). 2016 Mar;123(3):167-77. doi: 10.1007/s00702-015-1480-7. Epub 2015 Nov 6.
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Transplantation of human retinal pigment epithelium cells in the treatment for Parkinson disease.人视网膜色素上皮细胞移植治疗帕金森病。
CNS Neurosci Ther. 2012 Dec;18(12):1012-20. doi: 10.1111/cns.12025.

引用本文的文献

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Prosaposin maintains lipid homeostasis in dopamine neurons and counteracts experimental parkinsonism in rodents.原朊素在多巴胺神经元中维持脂质动态平衡，并对抗啮齿动物的实验性帕金森病。
Nat Commun. 2023 Sep 19;14(1):5804. doi: 10.1038/s41467-023-41539-5.
2
Intrastriatal transplantation of retinal pigment epithelial cells for the treatment of Parkinson disease: in vivo longitudinal molecular imaging with 18F-P3BZA PET/CT.视网膜色素上皮细胞脑内纹状体移植治疗帕金森病：18F-P3BZA PET/CT活体纵向分子成像
Radiology. 2014 Jul;272(1):174-83. doi: 10.1148/radiol.14132042. Epub 2014 Apr 20.

本文引用的文献

1
Intrastriatal transplantation of microcarrier-bound human retinal pigment epithelial cells versus sham surgery in patients with advanced Parkinson's disease: a double-blind, randomised, controlled trial.立体定向纹状体移植微载体结合的人视网膜色素上皮细胞与假手术治疗晚期帕金森病患者的随机双盲对照研究。
Lancet Neurol. 2011 Jun;10(6):509-19. doi: 10.1016/S1474-4422(11)70097-7. Epub 2011 May 10.
2
Placebo response in Parkinson's disease: comparisons among 11 trials covering medical and surgical interventions.帕金森病中的安慰剂反应：11项涵盖药物和手术干预试验的比较
Mov Disord. 2008 Apr 15;23(5):690-9. doi: 10.1002/mds.21894.
3
Characterization and survival of long-term implants of human retinal pigment epithelial cells attached to gelatin microcarriers in a model of Parkinson disease.
在帕金森病模型中，对附着于明胶微载体上的人视网膜色素上皮细胞长期植入物的表征及存活情况研究
J Neuropathol Exp Neurol. 2007 Jul;66(7):585-96. doi: 10.1097/nen.0b013e318093e53a.
4
Human retinal pigment epithelial cell implants ameliorate motor deficits in two rat models of Parkinson disease.人视网膜色素上皮细胞植入物可改善两种帕金森病大鼠模型的运动功能障碍。
J Neuropathol Exp Neurol. 2007 Jul;66(7):576-84. doi: 10.1097/nen.0b013e318093e521.
5
Intrastriatal implantation of human retinal pigment epithelial cells attached to microcarriers in advanced Parkinson disease.在晚期帕金森病中，将附着于微载体的人视网膜色素上皮细胞植入纹状体内。
Arch Neurol. 2005 Dec;62(12):1833-7. doi: 10.1001/archneur.62.12.1833.
6
PET imaging of implanted human retinal pigment epithelial cells in the MPTP-induced primate model of Parkinson's disease.在MPTP诱导的帕金森病灵长类动物模型中植入的人视网膜色素上皮细胞的PET成像。
Exp Neurol. 2004 Oct;189(2):361-8. doi: 10.1016/j.expneurol.2004.06.009.
7
Animal models of neurological deficits: how relevant is the rat?神经功能缺损的动物模型：大鼠的相关性如何？
Nat Rev Neurosci. 2002 Jul;3(7):574-9. doi: 10.1038/nrn877.
8
Striatal xenotransplantation of human retinal pigment epithelial cells attached to microcarriers in hemiparkinsonian rats ameliorates behavioral deficits without provoking a host immune response.在偏侧帕金森病大鼠中，将附着于微载体的人视网膜色素上皮细胞纹状体异种移植可改善行为缺陷，且不会引发宿主免疫反应。
Cell Transplant. 2002;11(3):207-14.