Ozden Feyza Otan, Gunduz Kaan, Ozden Bora, Isci K Devrim, Fisgin Tunc
Department of Periodontology, Faculty of Dentistry, Ondokuz Mayis University, Samsun, Turkey.
Eur J Dent. 2011 Jul;5(3):344-8.
Diamond-Blackfan Anemia (DBA) is a red cell aplasia characterized with physical abnormalities. The incidence of the disease is reported to be five to seven (5-7) cases per million births in Europe and 4-5 per million live births in the UK and Netherlands with equal sex ratio. It was first recognized in 1938 but an exact pathophysiology of the disease has not been described yet. These abnormalities are well known, however, detailed oral and dental conditions related with the disease have not been described previously. We herein presented two cases of DBA together with oral and dental findings. Our study is first to report the gingival status of the patients with a complete investigation of any orthodontic or dental abnormalities in these kind of patients. A careful follow up and preventive therapies should not be missed in these kind of patients.
先天性纯红细胞再生障碍性贫血（DBA）是一种伴有身体异常特征的红细胞再生障碍。据报道，该疾病在欧洲的发病率为每百万例出生中有5至7例，在英国和荷兰每百万例活产中有4至5例，男女比例相等。它于1938年首次被发现，但该疾病的确切病理生理学尚未得到描述。然而，这些异常是众所周知的，此前尚未描述与该疾病相关的详细口腔和牙齿状况。我们在此介绍两例DBA病例以及口腔和牙齿检查结果。我们的研究首次报告了对这类患者进行任何正畸或牙齿异常全面检查后的牙龈状况。对于这类患者，不应错过仔细的随访和预防性治疗。
