Turkbeyler Ibrahim Halil, Pehlivan Yavuz, Comez Gazi, Pehlivan Davut, Sevinc Alper, Kalender Mehmet Emin, Karakok Metin, Camci Celalettin
Gaziantep University Faculty of Medicine, Department of Internal medicine, Gaziantep, Turkey .
Tokai J Exp Clin Med. 2011 Jul 20;36(2):29-30.
Dubowitz syndrome was first described in 1965 by the English physician Dr. Victor Dubowitz. This genetic disorder causes growth retardation both before and after birth. It is primarily diagnosed through the distinctive facial features of affected individuals, including a small triangular-shaped face with a high forehead and wide-set, slitted eyes. The main method of diagnosis is through identification of facial phenotype. Esophageal mass biopsy revealed squamous cell carcinoma type. Both malignancy and IgA deficiency have been reported literature in patients with Dubowitz syndrome. However, Esophagus cancer has not been reported among the malignant tumors. Herein, we reported a patient with Dubowitz syndrome, IgA deficiency and Esophagus cancer.
杜波维茨综合征于1965年由英国医生维克多·杜波维茨博士首次描述。这种遗传性疾病会导致出生前后的生长发育迟缓。主要通过受影响个体独特的面部特征进行诊断，包括小三角形脸、高额和眼距宽且呈裂缝状的眼睛。主要诊断方法是通过识别面部表型。食管肿物活检显示为鳞状细胞癌类型。文献报道杜波维茨综合征患者存在恶性肿瘤和IgA缺乏。然而，食管癌在恶性肿瘤中尚未见报道。在此，我们报告了1例患有杜波维茨综合征、IgA缺乏和食管癌的患者。
