Zhao Zhen-Mei, Qin Shu-Cun
Taishan Medical College, Atherosclerosis Institute, Tai'an 271000, China.
Sheng Li Ke Xue Jin Zhan. 2011 Apr;42(2):86-90.
The major goal of atherosclerotic molecular imaging is to target specific plaque-associated molecules with molecular probe that provide sensitive and specific imaging contrast and acquire molecular imaging. This method will greatly improve detection and characterization of atherosclerotic lesions, especially plaque components. The plaque components are highly associated with plaque rupture and vulnerability to rupture as well as the consequences followed plaque rupture. Thus, the knowledge about plaque composition will have tremendous clinical utility in terms of the treatment and prognosis judgment of patients with atherosclerosis.
动脉粥样硬化分子成像的主要目标是用分子探针靶向特定的斑块相关分子，这些分子探针能提供敏感且特异的成像对比并获取分子影像。这种方法将极大地改善动脉粥样硬化病变的检测与特征描述，尤其是斑块成分。斑块成分与斑块破裂、破裂易感性以及斑块破裂后的后果高度相关。因此，关于斑块组成的知识在动脉粥样硬化患者的治疗和预后判断方面将具有巨大的临床应用价值。
