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秋水仙碱敏感的 AA 淀粉样变性肾病综合征。

Colchicine-sensitive nephrotic syndrome due to AA amyloidosis.

机构信息

Department of Nephrology, Soroka Medical Center and Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.

出版信息

Amyloid. 2011 Sep;18(3):169-71. doi: 10.3109/13506129.2011.594823. Epub 2011 Jul 20.

DOI:10.3109/13506129.2011.594823
PMID:21770831
Abstract

A 28-year-old women is presented who was evaluated for a new-onset postpartum nephrotic syndrome with normal renal function. Histological diagnosis was AA amyloidosis but no underlying disease has been diagnosed despite extensive workup. Complete remission was achieved with colchicine. Upon discontinuation of colchicines, the patient's nephrotic syndrome flared up but completely responded to reinstitution of colchicine therapy. Remission of this patient's nephrotic syndrome is thus not attributable to resolution of any "idiopathic" primary disease.

摘要

一位 28 岁女性,新诊断为产后肾病综合征,肾功能正常。组织学诊断为 AA 淀粉样变性,但尽管进行了广泛的检查,仍未发现潜在疾病。秋水仙碱治疗后达到完全缓解。停用秋水仙碱后,患者的肾病综合征复发,但重新开始秋水仙碱治疗后完全缓解。因此,该患者肾病综合征的缓解并非归因于任何“特发性”原发性疾病的解决。

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