Institute of Dentistry, University of Oulu, Oulu, Finland.
J Clin Periodontol. 2011 Sep;38(9):787-94. doi: 10.1111/j.1600-051X.2011.01758.x. Epub 2011 Jul 19.
The aim of this cross-sectional study was to investigate whether serum total cholesterol/high-density lipoprotein cholesterol (TC/HDL) ratio and low-density lipoprotein cholesterol/high-density lipoprotein cholesterol (LDL/HDL) ratio are associated with periodontal infection.
This study was based on a subpopulation of the Health 2000 Survey, which included dentate, non-diabetic subjects who had never smoked and who were aged between 30 and 49 years (n=1297). The numbers of teeth with deepened (4 mm deep or deeper) and with deep (6 mm deep or deeper) periodontal pockets were used as outcome variables, as well as the presence of gingival bleeding.
We found no consistent associations between TC/HDL or LDL/HDL ratios and the number of teeth with deepened periodontal pockets or the presence of gingival bleeding among normal weight subjects. Nor were there any consistent associations between TC/HDL or LDL/HDL ratios and the number of teeth with deepened periodontal pockets or the presence of gingival bleeding among subjects whose body mass index was 25 or more.
This study does not provide evidence that unfavourable lipid composition can be considered as an important risk for periodontal infection in a general adult population.
本横断面研究旨在探讨血清总胆固醇/高密度脂蛋白胆固醇（TC/HDL）比值和低密度脂蛋白胆固醇/高密度脂蛋白胆固醇（LDL/HDL）比值是否与牙周感染有关。
本研究基于健康 2000 调查的一个亚人群，该亚人群包括无糖尿病、从未吸烟且年龄在 30 至 49 岁之间的有牙者（n=1297）。用探诊深度为 4 毫米或更深的牙齿数量和探诊深度为 6 毫米或更深的牙齿数量作为因变量，同时还记录了牙龈出血情况。
我们发现，在正常体重受试者中，TC/HDL 或 LDL/HDL 比值与探诊深度为 4 毫米或更深的牙齿数量或牙龈出血之间不存在一致的关联。在 BMI 为 25 或以上的受试者中，TC/HDL 或 LDL/HDL 比值与探诊深度为 4 毫米或更深的牙齿数量或牙龈出血之间也不存在一致的关联。
本研究并未提供证据表明，不良的脂质组成可被视为一般成年人群中牙周感染的一个重要危险因素。
