Ollikainen Emilia, Saxlin Tuomas, Tervonen Tellervo, Suominen Anna Liisa, Knuuttila Matti, Jula Antti, Ylöstalo Pekka
Institute of Dentistry, University of Oulu, Oulu, Finland.
J Clin Periodontol. 2014 Dec;41(12):1132-8. doi: 10.1111/jcpe.12316. Epub 2014 Oct 27.
The aim of this cross-sectional study was to investigate whether periodontal condition is associated with hypertension and systolic blood pressure.
The study population consisted of dentate, non-diabetic, non-smoking individuals aged 30-49 years (n = 1296) in the national Health 2000 Survey in Finland. The number of teeth with deepened (≥4 mm) and deep (≥6 mm) periodontal pockets and the number of sextants with gingival bleeding were used as explanatory variables. Hypertension and systolic blood pressure were used as outcome variables.
There was no consistent association between the number of teeth with deepened (≥4 mm) (OR 0.98, 95% CI 0.95-1.01) or deep (≥6 mm) (OR 1.01, 95% CI 0.90-1.12) periodontal pockets and hypertension after adjusting for confounding factors. Nor was there any essential association between the number of bleeding sextants and hypertension.
Periodontal pocketing and gingival bleeding did not appear to be related to hypertension in non-diabetic, non-smoking individuals aged 30-49 years. Further studies using experimental study designs would be required to determine the role of infectious periodontal diseases in the development or progression of hypertension.
本横断面研究旨在调查牙周状况是否与高血压及收缩压相关。
研究人群包括芬兰全国健康2000调查中年龄在30 - 49岁的有牙、非糖尿病、不吸烟个体(n = 1296)。牙周袋加深(≥4毫米)和深度牙周袋(≥6毫米)的牙齿数量以及牙龈出血的牙区段数量用作解释变量。高血压和收缩压用作结果变量。
在调整混杂因素后,牙周袋加深(≥4毫米)(比值比0.98,95%可信区间0.95 - 1.01)或深度牙周袋(≥6毫米)(比值比1.01,95%可信区间0.90 - 1.12)的牙齿数量与高血压之间没有一致的关联。牙龈出血牙区段数量与高血压之间也没有任何本质关联。
在30 - 49岁的非糖尿病、不吸烟个体中,牙周袋形成和牙龈出血似乎与高血压无关。需要采用实验性研究设计进行进一步研究,以确定感染性牙周疾病在高血压发生或发展中的作用。