Scilletta A, Soma P F, Grasso G, Scilletta R, Pompili G, Tarico M S, Perrotta R E
Department of Plastic Surgery, University of Catania, Italia.
G Chir. 2011 Jun-Jul;32(6-7):323-5.
Primary mucinous carcinoma of the skin (MCS) is a rare neoplasia described for the first time by Lennox et al. in 1952 and formally reviewed by Mendoza and Helwing in 1971. It is an uncommon subtype of sweat gland tumor. MCS affects men (58,8%) more than women (41,2%). It tends to occur in more elderly individuals (average 62,6 years, range 8-87 years), although the disease has been reported in a patient as young as 8 years old. In the english Literature are described 100 case of MCS. MCS has a varied clinical onset, tipically presenting as an asymptomatic, slow-growning, painless, papular or nodular, subcutaneous or cutaneous, ranging from 5 mm to 120 mm. The lesion is frequently single and isolated red, pink, gray, blue or purple coulored. Telangiectasia may or not be present. The surface may be smooth, ulcerated or crusted. Local recurrence occurs frequently (29,4%) after conventional excision, but the rate of distant metastasis is low (9,6%). In fact this tumour is tipically avascular, a factor that help to explain its low rate of metastasis. In September 2007, a 69 year old white man was referred to our observation for the evaluation of a painless, superficial nodular mass in left cheek that had slowly grown over 1 year to 2x1,4 cm current measures. The lesion was excised. Microscopic examination revealed a mucinous cutaneous carcinoma of the skin. Investigations for a primary visceral malignancy, including CT total body and colonoscopy, were negative.
原发性皮肤黏液癌（MCS）是一种罕见的肿瘤，1952年由伦诺克斯等人首次描述，1971年门多萨和赫尔温进行了正式综述。它是汗腺肿瘤的一种不常见亚型。MCS男性患者（58.8%）多于女性患者（41.2%）。它倾向于发生在年龄较大的个体中（平均62.6岁，范围8 - 87岁），不过也有8岁患者的病例报道。英文文献中描述了100例MCS病例。MCS有多种临床发病表现，通常表现为无症状、生长缓慢、无痛、丘疹状或结节状、皮下或皮肤肿物，大小从5毫米到120毫米不等。病变通常为单个，颜色为红色、粉色、灰色、蓝色或紫色。可能有或没有毛细血管扩张。表面可能光滑、溃疡或结痂。传统切除后局部复发很常见（29.4%），但远处转移率较低（9.6%）。实际上，这种肿瘤通常无血管，这一因素有助于解释其低转移率。2007年9月，一名69岁的白人男性因左侧脸颊无痛性浅表结节状肿物前来我们处就诊，该肿物在1年时间里缓慢生长至目前的2×1.4厘米大小。病变被切除。显微镜检查显示为皮肤黏液癌。包括全身CT和结肠镜检查在内的原发性内脏恶性肿瘤检查均为阴性。
