在钠钾ATP酶适应性刺激过程中大鼠盲肠黏膜中环鸟苷酸水平降低。
Decreased cyclic GMP levels in rat cecum mucosa during adaptive stimulation of Na-K-ATPase.
作者信息
Grezer R, Loeschke K
出版信息
Experientia. 1979 Feb 15;35(2):197-9. doi: 10.1007/BF01920612.
PMID:217720
Abstract
In rat cecal mucosa, Na-K-ATPase specific activity and sodium and fluid absorption were increased by giving polyethylene glycol administration with the drinking water. Whereas cyclic AMP levels were unchanged, cyclic GMP was reduced by about 50%. This finding suggests a regulatory role of cyclic GMP in intestinal sodium and fluid absorption.
摘要
在大鼠盲肠黏膜中，通过在饮用水中给予聚乙二醇，钠钾ATP酶的比活性以及钠和液体的吸收增加。虽然环磷酸腺苷水平未变，但环磷酸鸟苷减少了约50%。这一发现表明环磷酸鸟苷在肠道钠和液体吸收中具有调节作用。
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