人乳头瘤病毒在支气管内乳头状鳞状肿瘤中的作用调查
An investigation into the role of human papillomavirus in endobronchial papillary squamous tumours.
作者信息
Carey F A, Salter D M, Kerr K M, Lamb D
机构信息
Department of Pathology, University of Edinburgh, U.K.
出版信息
Respir Med. 1990 Nov;84(6):445-7. doi: 10.1016/s0954-6111(08)80107-2.
Tissue specimens from 15 patients with endobronchial papillary squamous tumours were probed for the presence of human papillomavirus DNA using the technique of in situ hybridization with probes to human papillomavirus genotypes 4, 5, 6b, 8, 11, 16 and 18. Despite the histological similarity of these lesions to known human papillomavirus-associated tumours no evidence of hybridization was detected in any of the cases analysed. It is thus unlikely that human papillomavirus has a significant role in the genesis of these tumours.
采用与人类乳头瘤病毒4型、5型、6b型、8型、11型、16型和18型探针进行原位杂交技术，对15例支气管内乳头状鳞状肿瘤患者的组织标本检测人类乳头瘤病毒DNA的存在情况。尽管这些病变在组织学上与已知的人类乳头瘤病毒相关肿瘤相似，但在分析的任何病例中均未检测到杂交证据。因此，人类乳头瘤病毒在这些肿瘤的发生过程中不太可能起重要作用。
Zotero 插件