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眼眶应力分析:第三部分:使用生物可吸收聚-L/DL-丙交酯(P[L/DL]LA 70:30)植入物修复眼眶爆裂性骨折的生物力学

Orbital stress analysis: part III: biomechanics of orbital blowout fracture repair using bioresorbable poly-L/DL-lactide (P[L/DL]LA 70:30) implant.

作者信息

Al-Sukhun Jehad, Penttilä Heikki, Ashammakhi Nureddin

机构信息

Department of Oral and Maxillofacial Surgery, Euro-Oral Hammaslääkärikeskus Fredrikinkatu, Helsinki, Finland.

出版信息

J Craniofac Surg. 2011 Jul;22(4):1299-303. doi: 10.1097/SCS.0b013e31821c6ae9.

Abstract

PURPOSE OF THE STUDY

The purpose was to study the biomechanics of bone fracture repair, of the orbital floor, using osteosynthetic bioresorbable implant and how to improve the implant design.

MATERIALS AND METHODS

A finite element model of the orbit and the globe of 1 patient who experienced orbital blowout fracture and treated with bioresorbable poly-L/DL-lactide (P[L/DL]LA 70:30) implant (PolyMax; Synthes, Oberdorf, Switzerland) was generated based on computed tomographic scans. Simulations were performed with a computer using a commercially available finite element software. The effects of changing the geometry, bony support, and method of fixation of the implant on the finite element model predictions were investigated.

RESULTS

The factor that had the biggest impact on the predicted principal strain magnitudes was absence of bony support of the implant (up to 65%). Applying elastic fixation reduced stresses (up to 40%) posteriorly. The principal stresses inside the bone and the implant were evenly distributed when elastic fixation was applied to the implant. Applying rigid fixation increased stresses (up to 50% and 80% anteriorly and posteriorly, respectively). The resulting stress values indicated a likely rapid failure of the osteosynthetic implant when rigid fixation was applied.

CONCLUSIONS

Applying rigid fixation induced a significant increase in stress patterns. Principal stresses were reduced remarkably when elastic fixation was applied to the implant. The role of fixation becomes more prominent when there is no bony support posteriorly and/or medially. It is recommended to avoid rigid fixation and to apply elastic fixation when using bioresorbable P(L/DL)LA 70:30 implants to reconstruct inferior orbital wall bony defects.

摘要

研究目的

本研究旨在利用可吸收骨植入物研究眼眶底骨折修复的生物力学,以及如何改进植入物设计。

材料与方法

基于计算机断层扫描,建立了1例眼眶爆裂性骨折患者使用可吸收聚-L/DL-丙交酯(P[L/DL]LA 70:30)植入物(PolyMax;Synthes,瑞士奥伯多夫)治疗后的眼眶和眼球有限元模型。使用商用有限元软件在计算机上进行模拟。研究了改变植入物的几何形状、骨支撑和固定方法对有限元模型预测结果的影响。

结果

对预测主应变大小影响最大的因素是植入物缺乏骨支撑(高达65%)。采用弹性固定可降低后方应力(高达40%)。对植入物采用弹性固定时,骨和植入物内部的主应力分布均匀。采用刚性固定会增加应力(前方和后方分别高达50%和80%)。所得应力值表明,采用刚性固定时,骨合成植入物可能会迅速失效。

结论

采用刚性固定会导致应力模式显著增加。对植入物采用弹性固定时,主应力会显著降低。当后方和/或内侧没有骨支撑时,固定的作用更为突出。建议在使用可吸收P(L/DL)LA 70:30植入物重建眶下壁骨缺损时避免刚性固定,采用弹性固定。

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