Marques Rita, Martins Cristina, Machado Inês, Monteiro José Paulo, Campos Nuno, Calhau Paulo
Pediatric Department, Hospital Garcia da Orta, Almada, Portugal;
Pediatr Rep. 2011 Jun 16;3(2):e11. doi: 10.4081/pr.2011.e11.
Neurobrucellosis manifesting as optic neuritis is a rare disease in childhood. We report a case of neurobrucellosis in a 11 year old girl leading to visual impairment and headache. Physical examination revealed mild oedema of right tibiotarsic joint and optic neuritis. Investigations showed CSF pleocytosis and a Brucella serum agglutination titer of 1/640. Complete reversal of the symptoms was observed after appropriate antibiotic treatment. To our knowledge only four cases of neurobrucellosis manifesting with visual impairment in childhood are previously reported in literature.
表现为视神经炎的神经型布鲁氏菌病在儿童中是一种罕见疾病。我们报告一例11岁女孩的神经型布鲁氏菌病,该病导致视力损害和头痛。体格检查发现右胫跗关节轻度水肿和视神经炎。检查显示脑脊液细胞增多,布鲁氏菌血清凝集效价为1/640。经适当抗生素治疗后症状完全缓解。据我们所知,此前文献中仅报道过4例儿童期表现为视力损害的神经型布鲁氏菌病病例。