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Efficacy and tolerability of antibiotic combinations in neurobrucellosis: results of the Istanbul study.神经布鲁氏菌病中抗生素联合用药的疗效和耐受性:伊斯坦布尔研究的结果。
Antimicrob Agents Chemother. 2012 Mar;56(3):1523-8. doi: 10.1128/AAC.05974-11. Epub 2011 Dec 12.
2
Unilateral optic neuritis as a presentation of neurobrucellosis.单侧视神经炎作为神经型布鲁氏菌病的一种表现形式。
Pediatr Rep. 2011 Jun 16;3(2):e11. doi: 10.4081/pr.2011.e11.
3
Neurobrucellosis associated with syndrome of inappropriate antidiuretic hormone with resultant diabetes insipidus and hypothyroidism.神经布鲁氏菌病伴抗利尿激素分泌不当综合征,导致尿崩症和甲状腺功能减退。
J Clin Microbiol. 2010 Oct;48(10):3806-9. doi: 10.1128/JCM.00721-10. Epub 2010 Aug 11.
4
Idiopathic intracranial hypertension.特发性颅内高压
BMJ. 2010 Jul 7;341:c2836. doi: 10.1136/bmj.c2836.
5
Neurobrucellosis: report of a rare disease in 20 Iranian patients referred to a tertiary hospital.神经型布鲁氏菌病:20例转诊至三级医院的伊朗患者的罕见疾病报告
East Mediterr Health J. 2009 Jan-Feb;15(1):143-8.
6
Overview of neurobrucellosis: a pooled analysis of 187 cases.神经型布鲁菌病概述:187 例汇总分析。
Int J Infect Dis. 2009 Nov;13(6):e339-43. doi: 10.1016/j.ijid.2009.02.015. Epub 2009 May 9.
7
Clinical and laboratory findings in neurobrucellosis: review of 31 cases.神经型布鲁氏菌病的临床与实验室检查结果:31例病例回顾
Arch Iran Med. 2008 Jan;11(1):21-5.
8
Abducens nerve palsy and optic neuritis as initial manifestation in brucellosis.布鲁氏菌病以展神经麻痹和视神经炎为首发表现
Scand J Infect Dis. 2006;38(8):721-5. doi: 10.1080/00365540500466614.
9
Neurobrucellosis as an exceptional cause of transient ischemic attacks.神经型布鲁氏菌病作为短暂性脑缺血发作的罕见病因。
Eur J Neurol. 2006 May;13(5):544-8. doi: 10.1111/j.1468-1331.2006.01286.x.
10
Acute meningitis due to Brucella spp.布鲁氏菌属所致急性脑膜炎
Eur J Pediatr. 2006 Oct;165(10):726-7. doi: 10.1007/s00431-006-0158-4. Epub 2006 May 12.

一名患有复发性短暂性脑缺血发作和假性脑瘤的儿童的神经型布鲁氏菌病罕见表现(病例报告及文献综述)

A Rare presentation of neurobrucellosis in a child with Recurrent transient ischemic attacks and pseudotumor cerebri (A case report and review of literature).

出版信息

Iran J Child Neurol. 2014 Spring;8(2):65-9.

PMID:24949055
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4058069/
Abstract

Brucellosis is a multi-system infectious disease that presents with various manifestations and complications. Neurobrucellosis is an uncommon but serious presentation of brucellosis that can be seen in all stages of the disease. High index of suspicion, especially in endemic areas is essential to prevent morbidity from this disease. The case was an 11- year -old female patient who was admitted with a severe headache that was worsening over a period of 2 months. The day after each attack, she experienced transient right hemiparesia that was lasting less than one hour (TIA) as well as blurred vision and bilateral papilledema. Laboratory findings revealed serum agglutination Wright test positive at 1/320 and 2ME test positive at 1/160. A lumbar puncture showed a clear CSF with increased opening pressure (32 cmH2O), CSF examination was within normal range (pseudotumor cerebri).To our knowledge, there has been no report for recurrent TIA in pediatric neurobrucellosis in the base of pseudotumor cerebri. In endemic areas like Iran, unexplained neurological signs or symptoms should be evaluated for brucellosis.

摘要

布鲁氏菌病是一种多系统传染病,有多种表现形式和并发症。神经型布鲁氏菌病是布鲁氏菌病的一种罕见但严重的表现形式,可在疾病的各个阶段出现。高度怀疑,尤其是在流行地区,对于预防这种疾病的发病至关重要。该病例为一名11岁女性患者,因严重头痛入院,头痛在2个月内逐渐加重。每次发作后的第二天,她会出现持续不到一小时的短暂性右侧偏瘫(短暂性脑缺血发作)以及视力模糊和双侧视乳头水肿。实验室检查结果显示血清凝集试验(Wright试验)1/320呈阳性,2-巯基乙醇试验(2ME试验)1/160呈阳性。腰椎穿刺显示脑脊液清澈,初压升高(32cmH₂O),脑脊液检查在正常范围内(假脑瘤)。据我们所知,在假脑瘤基础上的小儿神经型布鲁氏菌病复发性短暂性脑缺血发作尚无报告。在伊朗等流行地区,对于不明原因的神经体征或症状,应评估是否为布鲁氏菌病。