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[伴有中毒性休克样综合征的坏死性筋膜炎。病例报告]

[Necrotizing fasciitis with toxic shock-like syndrome. Case report].

作者信息

Chen Y M, Tarng D C, Wang L S

机构信息

Department of Chest, Veterans General Hospitcal-Taipei, R.O.C.

出版信息

Zhonghua Yi Xue Za Zhi (Taipei). 1990 Aug;46(2):117-20.

PMID:2177364
Abstract

Fulminant group A streptococcal infection with necrotizing fasciitis and toxic shock-like syndrome is rare in Taiwan. We had diagnosed a case of necrotizing fasciitis with toxic shock-like syndrome in January, 1990. Tracing the patient's history, he was rather well in the past except that he scratched his skin occasionally. Erythromatous change with swelling and painful sensation of skin over medial aspect of left thigh was noted 4 days before admission. He called on local dermatologist and was treated with some topical medication. Unfortunately, the condition went downhill within 2 days with the lesion extending to the scrotum and causing vesicular formation and necrotic change of the skin over left thigh and scrotum. He was sent to our Emergency Room in shock condition and was admitted under impression of necrotizing fasciitis with septic shock. Incision and drainage was done in the second hospital day and group A streptococcus was isolated from blood and skin later. His condition became stable slowly. Due to extensive necrosis of skin and subcutaneous tissue, debridement had been done twice and skin graft was done one month after admission. We report this case to emphasise the rare but fulminant nature of group A streptococcal necrotizing fasciitis with toxic shock-like syndrome and the importance of early surgical and medical management.

摘要

暴发性A群链球菌感染合并坏死性筋膜炎及中毒性休克样综合征在台湾较为罕见。我们于1990年1月诊断出1例坏死性筋膜炎合并中毒性休克样综合征的病例。追溯患者病史,他既往身体状况良好,只是偶尔会抓挠皮肤。入院前4天,发现左大腿内侧皮肤出现红斑,伴有肿胀和疼痛。他前往当地皮肤科医生处就诊,接受了一些外用药物治疗。不幸的是,病情在2天内恶化,病变蔓延至阴囊,导致左大腿和阴囊皮肤出现水疱形成及坏死改变。他以休克状态被送往我们的急诊室,入院诊断为坏死性筋膜炎合并感染性休克。在入院第二天进行了切开引流,随后从血液和皮肤中分离出A群链球菌。他的病情逐渐稳定。由于皮肤和皮下组织广泛坏死,进行了两次清创术,并在入院后1个月进行了皮肤移植。我们报告该病例以强调A群链球菌坏死性筋膜炎合并中毒性休克样综合征这种罕见但暴发性的疾病,以及早期手术和药物治疗的重要性。

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