[Computer study of pathologic factors influencing survival in colorectal carcinoma--a multivariant stepwise discriminant analysis].

Five quantitative pathologic parameters and three clinicopathologic parameters in 80 colorectal carcinoma patients with different prognosis were studied with a multivariant stepwise discriminant analysis on computer. The results showed that DNA index (DI), nucleocytoplasmic ratio (NCR), histologic grade and Dukes' stage were significant factors influencing the survival. With these factors, a 4-variable Fisher's discriminant function was established, which could correctly identify 81.25% and 83.75% of the predicted cases (Jacknife Procedure and Reclassification) Sensitivity of the two methods was 87.80%. The results indicate that the multivariant stepwise discriminant analysis on quantitative pathologic parameters combined with clinicopathologic parameters is of value in predicting prognosis of colorectal carcinoma patients.