Yi Qiangying, Liu Kang, Feng Gang
Institute of Tissue Engineering and Stem Cells, The Second Clinical Institute of North Sichuan Medical College, Nanchong 637000, China.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2011 Jun;28(3):627-31.
Disc degeneration disease (DDD) is the major cause of lower back pain, resulting in significant serious social problems and economic burdens due to its high mortality rate and disability rate. Currently available clinic treatments are inefficient for solving spinal structure and function insufficiency caused by the DDD, especially for patients with degenerated or broken anulus fibrosus. Tissue engineering provides a promising and available strategy to regenerate a new anulus fibrosus with complete bio-functions. This review following primary introduces the current research progress and the potential development orientation of tissue engineering anulus fibrosus.
椎间盘退变疾病（DDD）是下背痛的主要原因，因其高死亡率和致残率而导致严重的社会问题和经济负担。目前可用的临床治疗方法在解决由DDD引起的脊柱结构和功能不足方面效率低下，特别是对于纤维环退变或破裂的患者。组织工程提供了一种有前景且可行的策略，以再生具有完整生物功能的新纤维环。本综述首先介绍了组织工程纤维环的当前研究进展和潜在的发展方向。
